Rejuran – advanced skin regeneration with polynucleotides. Professional insight for aesthetic experts
Rejuran explained – science meets aesthetics
Rejuran is a pioneering treatment concept based on polynucleotides (PN) – long DNA fragments obtained from salmon, a species with DNA sequences very close to human. Their therapeutic power lies in:
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activating fibroblasts to produce new collagen and elastin,
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restoring microcirculation and supporting vascular growth,
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protecting skin cells from oxidative stress,
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providing anti-inflammatory and tissue repair activity,
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improving texture, elasticity and overall skin density.
This makes Rejuran not just a cosmetic enhancer, but a biological skin healer.
The Rejuran portfolio – tailored solutions for specific concerns
Rejuran Healer
The original and most widely used formula, focused on overall dermal repair. Ideal for patients with fine lines, uneven texture, and early loss of elasticity.
Rejuran S
Specialized for acne scar correction. Thanks to its thicker consistency, it fills depressed scars and stimulates long-term tissue regeneration.
Rejuran I
Formulated for the periorbital area, where skin is thinner and more delicate. Reduces fine wrinkles, dark circles, and laxity without the heaviness of fillers.
Rejuran HB
Combines hyaluronic acid with PN for patients suffering from dehydration and dullness. Provides hydration and regeneration simultaneously.
Rejuran Tone-Up
Targets pigmentation and uneven skin tone. Enhances radiance while stimulating structural renewal.
Biological impact – what makes Rejuran different?
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DNA protection and cellular repair: defending against oxidative stress and UV-related damage.
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Collagen stimulation: increasing dermal thickness for lasting firmness.
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Natural compatibility: salmon DNA fragments are safe, non-immunogenic, and well tolerated.
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Comprehensive rejuvenation: treating not just wrinkles, but the cause of skin aging at the cellular level.
Documented results – clinical outcomes
Published studies and practice data confirm:
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measurable improvement in skin elasticity by 15–25%,
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wrinkle depth reduction of up to 30%,
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visible scar improvement after 3–4 sessions,
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hydration increase and brighter complexion.
Treatment protocols with Rejuran
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Administration: microinjections using mesotherapy techniques.
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Treatment plan: usually 3–4 sessions every 3–4 weeks.
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Synergy: can be combined with botulinum toxin, hyaluronic acid fillers, microneedling, or energy-based devices.
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Downtime: minimal, with only temporary redness or small papules.
Safety and patient satisfaction
Rejuran is recognized for its excellent safety profile. Due to its natural origin and purification process, the risk of allergy is extremely low. Side effects are transient and limited to injection-related reactions.
Long-term results – smoother skin, improved tone and elasticity – can last 12–18 months.
How Rejuran compares with other treatments
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Profhilo – bioremodeling and hydration, but without DNA-level repair.
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Sunekos – collagen stimulation via HA and amino acids, with shorter longevity.
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PRP – patient’s own plasma, highly individual in results.
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Rejuran – combines scientific consistency with long-lasting regeneration.
Indications and patient selection
Rejuran is recommended for:
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patients in their late 20s and above, with early or advanced aging signs,
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individuals with acne scars or uneven texture,
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dehydrated, fragile or UV-damaged skin,
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patients preferring natural regeneration over volumizing fillers.
Contraindications: pregnancy, breastfeeding, active skin infections, autoimmune conditions.
Patient FAQs
Is the treatment painful?
Minimal discomfort, with numbing cream applied before injection.
When will results show?
Most patients notice improvements after the second session, with full benefits visible in 2–3 months.
How many treatments are needed?
A protocol of 3–4 sessions is standard, followed by maintenance once or twice a year.
Can it be combined with fillers or toxins?
Yes – Rejuran enhances skin quality while other injectables focus on volume and muscle relaxation.
Conclusion – why choose Rejuran from Dermafiller.shop?
Rejuran represents a new generation of regenerative aesthetics – one that goes beyond temporary solutions and restores skin health at its foundation. With a proven track record of safety and efficacy, it is trusted by leading clinics worldwide.
👉 Discover the full Rejuran range on Dermafiller.shop and integrate one of the most advanced biostimulators into your clinical practice today.